Motif ID: FOX{I1,J2}.p2

Z-value: 1.550


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
Foxi1 14233 forkhead box I1
Foxj2 60611 forkhead box J2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj2chr6_+_1227702010.368.4e-07Click!
Foxi1chr11_-_341080530.199.3e-03Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_32557916 64.362 NM_021319
 Pglyrp2
peptidoglycan recognition protein 2
chr17_-_32557807 59.379 Pglyrp2
peptidoglycan recognition protein 2
chr15_+_103284200 37.257 NM_153505
 Nckap1l
NCK associated protein 1 like
chr10_-_61960613 31.104 Srgn
serglycin
chr15_+_83393975 28.805 NM_009775
 Tspo
translocator protein
chr2_-_27118325 28.310 Vav2
vav 2 oncogene
chr6_-_48658211 28.282 NM_153175
 Gimap6
GTPase, IMAP family member 6
chr18_-_35900005 24.786 NM_028261
 Tmem173
transmembrane protein 173
chr2_+_24242134 24.700 Psd4
pleckstrin and Sec7 domain containing 4
chr12_-_80084464 24.197 NM_001170401
 Tmem229b
transmembrane protein 229B
chr14_-_56407622 23.882 NM_001164107
NM_001164108
NM_019955
 Ripk3


receptor-interacting serine-threonine kinase 3


chr12_-_27141303 23.575 NM_021384
 Rsad2
radical S-adenosyl methionine domain containing 2
chr13_-_56280161 23.033 NM_001168615
NM_145976
 Tifab

TRAF-interacting protein with forkhead-associated domain, family member B

chr5_+_86500770 22.756 NM_019992
 Stap1
signal transducing adaptor family member 1
chr11_+_87569075 21.941 A430104N18Rik
RIKEN cDNA A430104N18 gene
chr5_-_73127743 21.538 NM_013698
 Txk
TXK tyrosine kinase
chr17_+_34442837 21.292 H2-Eb1
histocompatibility 2, class II antigen E beta
chr7_+_134439804 20.348 NM_008400
 Itgal
integrin alpha L
chr6_-_48658182 20.286 Gimap6
GTPase, IMAP family member 6
chr1_+_173847645 19.462 NM_030710
 Slamf6
SLAM family member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
Enrichment   P-value GO Accession GO Term
1.61 2.18e-02 GO:0080134 regulation of response to stress
1.46 2.32e-03 GO:0002376 immune system process
1.34 9.47e-04 GO:0006351 transcription, DNA-dependent
1.33 1.11e-03 GO:0032774 RNA biosynthetic process
1.32 4.97e-05 GO:0006355 regulation of transcription, DNA-dependent
1.30 1.45e-04 GO:0051252 regulation of RNA metabolic process
1.29 3.02e-05 GO:0009889 regulation of biosynthetic process
1.29 6.80e-05 GO:0010468 regulation of gene expression
1.29 1.59e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.28 7.47e-05 GO:0031326 regulation of cellular biosynthetic process
1.28 4.43e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.28 1.81e-03 GO:0016070 RNA metabolic process
1.27 5.13e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 1.04e-03 GO:0010467 gene expression
1.26 4.46e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.25 3.97e-03 GO:0090304 nucleic acid metabolic process
1.24 9.85e-06 GO:0019222 regulation of metabolic process
1.24 1.30e-04 GO:0080090 regulation of primary metabolic process
1.23 3.52e-04 GO:0060255 regulation of macromolecule metabolic process
1.22 7.95e-04 GO:0006807 nitrogen compound metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
1.71 8.17e-04 GO:0005730 nucleolus
1.45 1.16e-02 GO:0044451 nucleoplasm part
1.41 5.27e-06 GO:0031981 nuclear lumen
1.38 2.59e-06 GO:0044428 nuclear part
1.35 2.09e-02 GO:0005654 nucleoplasm
1.34 1.21e-04 GO:0070013 intracellular organelle lumen
1.34 1.41e-04 GO:0043233 organelle lumen
1.33 2.51e-04 GO:0031974 membrane-enclosed lumen
1.22 7.23e-08 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
2.47 2.07e-02 GO:0008026 ATP-dependent helicase activity
2.47 2.07e-02 GO:0070035 purine NTP-dependent helicase activity
1.45 1.01e-03 GO:0030528 transcription regulator activity
1.40 4.14e-02 GO:0001071 nucleic acid binding transcription factor activity
1.40 4.14e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.29 3.36e-03 GO:0003677 DNA binding
1.25 9.31e-04 GO:0003676 nucleic acid binding
1.09 1.86e-04 GO:0005488 binding